Methadone Heroin

Question by Gordon Cook: Need info on the drug “Subutex”?
Hey, so I took some subutex last night not knowing what it was at the time, thought it was E and got pretty messy. Ended up puking through-out the night and gouching out (really drowzy, in your own world) and began scratching. Morning after I have been puking up again especially if I drink anything, i’ve stopped being sick now however I still keep scratching. Everything on my body is being itchy. Basically is this a common side effect or have I had an allergic reaction? I feel overall ill and my eyes are black. I am not a heroine addict or addicted to methadone. If it helps I did snort a fair few lines since I did not feel anything after the first line, was it an overdose? Please don’t tell me how stupid I am for doing it or taking drugs, i’m not asking for your personal opinion on my life decisions. If you have an appropriate answer to this question I would very much appreciate it. Thanks!

Best answer:

Answer by Man
Buprenorphine (Subutex, Temgesic, or Suboxone [buprenorphine:naloxone 4:1 preparation] – sublingual tablets – Buprenex – for injection – and Norspan – transdermal patch) is a semi-synthetic opioid that is used to treat opioid addiction in higher dosages (>2 mg) and to control moderate pain in non-opioid tolerant individuals in lower dosages (~200 µg).

Buprenorphine is a Bentley-derivative opioid of the phenanthrene-morpholine class with extremely high binding affinity at the µ- and ?-opioid receptor. It has partial agonist activity at the µ-opioid receptor, partial or full agonist activity at the ORL1/nociceptin and ?-opioid receptor, and competitive antagonist activity at the ?-opioid receptor. Buprenorphine hydrochloride was first marketed in the 1980s by Reckitt & Colman (now Reckitt Benckiser) as an analgesic, available generally as Temgesic 0.2 mg sublingual tablets, and as Buprenex in a 0.3 mg/ml injectable formulation. In October 2002, the Food and Drug Administration (FDA) of the United States additionally approved Suboxone and Subutex, buprenorphine’s high-dose sublingual pill preparations indicated for detoxification and long-term replacement therapy in opioid dependency, and the drug is now used predominantly for this purpose. In the European Union, Suboxone and Subutex, buprenorphine’s high-dose sublingual pill preparations, were approved for opioid addiction treatment in September 2006. In the Netherlands, Buprenorphine is a List II drug of the Opium Law, though special rules and guidelines apply to its prescription and dispensation. In the USA, it has been a Schedule III drug under the United Nations’ Convention on Psychotropic Substances since it was rescheduled from Schedule V just before FDA approval of Suboxone and Subutex.[2] In recent years, buprenorphine has been introduced in most European countries as a transdermal formulation for the treatment of chronic pain.

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